Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PYGM | P11217 | 10/20 | 0.37 |
| ▸ | PYGL | P06737 | 10/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537068 | 0.90 | AKR1C3 (0.37) | POLBHSD17B10TDP1AKR1C3ALDH1A1 | |
| SCHEMBL5267430 | 0.89 | POLB (0.48) | POLBPYGMPYGLCDC25ACDC25B | |
| SCHEMBL4675279 | 0.85 | PYGL (0.36) | POLBPYGMPYGLCDC25ACDC25B | |
| SCHEMBL8911079 | 0.74 | HTT (0.36) | POLBHSD17B10MCL1AKR1C3ALDH1A1 | |
| SCHEMBL9750703 | 0.73 | PBRM1 (0.42) | POLBAKR1C3ALDH1A1 | |
| SCHEMBL1627984 | 0.71 | MAOA (0.36) | — | |
| SCHEMBL4649901 | 0.70 | POLB (0.41) | POLBPYGMPYGLCDC25ACDC25B | |
| SCHEMBL29404149 | 0.70 | PYGL (0.53) | POLBPYGMPYGLCDC25ACDC25B | |
| SCHEMBL716921 | 0.70 | PYGL (0.53) | POLBPYGMPYGLCDC25ACDC25B | |
| Ammonia Solution, Strong SCHEMBL10582921 | 0.70 | MAOA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963432-A1 | EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS | General Electric Company (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007078737-A1 | EXPANDED AND EXPANDABLE HIGH GLASS TRANSITION TEMPERATURE POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2007-07-12 | — | — | WO | disclosed |