Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5199562 | 0.98 | TSHR (0.38) | TSHRALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL3342681 | 0.81 | TSHR (0.44) | TSHRALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL5201169 | 0.80 | TSHR (0.33) | TSHRALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL19039332 | 0.80 | POLB (0.36) | ALDH1A1POLBKDM4E | |
| SCHEMBL28313237 | 0.74 | — | — | |
| SCHEMBL3447337 | 0.74 | ALPL (0.47) | TP53LMNAPOLBKDM4ENPC1 | |
| SCHEMBL22247554 | 0.74 | NCF1 (0.34) | ALDH1A1KDM4ENPC1 | |
| SCHEMBL5201371 | 0.74 | TDP1 (0.50) | TSHRALDH1A1CYP3A4TDP1TP53 | |
| SCHEMBL2771925 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1TDP1KDM4ENPC1 | |
| SCHEMBL5111323 | 0.74 | NOTUM (0.36) | LMNAPOLBNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108495613-A | composition for treating hair | 欧莱雅 | 2018-09-04 | — | — | CN | disclosed |
| CN-108472235-A | The composition for including heterocycle oxidation base and 2- amino -5- ethyl -phenol colour couplers for hair dyeing | 莱雅公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-1904442-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007005503-A1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-01-11 | — | — | WO | disclosed |
| EP-1274390-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A 3,5-DIAMINO-PYRIDINE DERIVATIVE AND A CATIONIC OR AMPHOTERIC POLYMER | L'OREAL (FR) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078669-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A 3,5-DIAMINO-PYRIDINE DERIVATIVE AND A CATIONIC OR AMPHOTERIC POLYMER | L'OREAL (FR) | 2001-10-25 | — | — | WO | disclosed |