Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649910 | 0.80 | TSHR (0.39) | TSHRLMNAKDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5199562 | 0.78 | TSHR (0.38) | TSHRLMNAPOLBALDH1A1CYP3A4 | |
| SCHEMBL3342681 | 0.74 | TSHR (0.44) | TSHRLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5199499 | 0.74 | — | — | |
| SCHEMBL19039332 | 0.73 | POLB (0.36) | MAPK8KDM4EPOLBRAB9AALDH1A1 | |
| SCHEMBL28313237 | 0.69 | — | — | |
| SCHEMBL22247554 | 0.69 | NCF1 (0.34) | KDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5201371 | 0.69 | TDP1 (0.50) | TSHRLMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL3447337 | 0.69 | ALPL (0.47) | LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL2771925 | 0.68 | ALDH1A1 (0.43) | TSHRKDM4ERAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |