Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650004 | 0.91 | CCR2 (0.54) | CCR9CCR2 | |
| SCHEMBL4650663 | 0.89 | CCR2 (0.55) | CCR9CCR2 | |
| SCHEMBL4649957 | 0.88 | CCR2 (0.53) | CCR9CCR2 | |
| SCHEMBL4648818 | 0.85 | CCR2 (0.53) | CCR9CCR2 | |
| SCHEMBL4748723 | 0.84 | PTGES (0.51) | CCR2 | |
| SCHEMBL4807606 | 0.83 | CCR2 (0.51) | CCR2 | |
| SCHEMBL4649909 | 0.83 | CCR2 (0.50) | CCR2 | |
| SCHEMBL4649594 | 0.81 | CCR2 (0.48) | CCR2 | |
| SCHEMBL4653137 | 0.80 | CCR2 (0.47) | CCR2 | |
| SCHEMBL4649469 | 0.78 | CCR2 (0.55) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904487-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006067392-A2 | INDOLE DERIVATIVES FOR THE TREATMENT OF TUBERCULOSIS | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |