Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650959 | 0.76 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL1452656 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL1453356 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL1453748 | 0.73 | TERT (0.35) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL1453097 | 0.73 | ALDH1A1 (0.32) | ALDH1A1TSHRALOX15HSD17B10TERT | |
| SCHEMBL4651925 | 0.73 | ALDH1A1 (0.34) | ALDH1A1HSD17B10APPMAPT | |
| SCHEMBL4652087 | 0.72 | L3MBTL1 (0.32) | MAPT | |
| SCHEMBL4653331 | 0.71 | — | — | |
| SCHEMBL4652089 | 0.70 | QDPR (0.35) | MAPT | |
| SCHEMBL4651188 | 0.69 | CYP3A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |