SCHEMBL465351

SCHEMBL465351

CC(C)Oc1ccc(Nc2ccc(C(C)(C)c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
LMNA P02545 3/20 0.47
GAA P10253 2/20 0.47
TP53 P04637 2/20 0.47
NR3C2 P08235 2/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
ACP1 P24666 1/20 0.44
KDM4E B2RXH2 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPY2R P49146 1/20 0.43
CYP3A4 P08684 2/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
GLA P06280 1/20 0.41
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39108 0.84 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL158574 0.82 NR3C2 (0.60) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL10934190 0.82 ALDH1A3 (0.48) ALDH1A1KMT2AMEN1LMNATP53
SCHEMBL1576428 0.80 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL2723103 0.80 GLA (0.57) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL8626323 0.78 ALDH1A1 (0.62) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL14136110 0.78 NR3C2 (0.49) ALDH1A1KMT2AMEN1LMNANR3C2
SCHEMBL7692657 0.77 RAB9A (0.55) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL11578590 0.77 ALDH1A1 (0.52) ALDH1A1KMT2AMEN1LMNAGAA
SCHEMBL471147 0.77 NR3C2 (0.55) ALDH1A1KMT2AMEN1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4015550-A1 THERMOPLASTIC COMPOSITIONS WITH GOOD MECHANICAL PROPERTIES Covestro Deutschland AG (DE) 2022-06-22 EP disclosed
EP-3919564-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
EP-3919562-A1 POLYAMIDE-BASED PRODUCTS LANXESS Deutschland GmbH (DE) 2021-12-08 EP disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
EP-2553021-B1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2014-05-07 EP disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
WO-2012007301-A3 FOAM ENHANCEMENT OF FATTY ACYL GLYCINATE SURFACTANTS UNILEVER PLC (GB) 2012-05-10 WO disclosed
EP-2257597-B1 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2011-11-30 EP disclosed
EP-2121843-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2009-11-25 EP disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
EP-2049597-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2009-04-22 EP disclosed
WO-2008074687-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2008-06-26 WO disclosed
WO-2008012233-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2008-01-31 WO disclosed
WO-2006100248-A2 THERMOPLASTIC MOLDING COMPOUNDS WITH INCREASED DIMENSIONAL STABILITY BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO disclosed
EP-0586985-B1 Stabilized Polyamide/Polyphenylene ether mouldings BASF AG (DE) 1996-12-18 EP disclosed
EP-0509282-B1 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF AG (DE) 1996-07-24 EP disclosed
EP-0509282-A2 Stabilized thermoplastic partly aromatic polyamide moulding compounds BASF Aktiengesellschaft (DE) 1992-10-21 EP disclosed
US-3944492-A Lubricant compositions containing N-substituted naphthylamines as antioxidants UNIROYAL, INC. (US) 1976-03-16 US disclosed