Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414397 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL5161276 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL13785277 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL13785278 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL7356506 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRKCNN4PTPN1NR1H2 | |
| SCHEMBL1401085 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHRKCNN4PTPN1NR1H2 | |
| SCHEMBL4080546 | 0.76 | KCNN4 (0.44) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL17091567 | 0.75 | KCNN4 (0.34) | ALDH1A1TSHRCES1KCNN4PTPN1 | |
| SCHEMBL7873896 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRCES1KCNN4MAPK1 | |
| SCHEMBL1229735 | 0.71 | CES1 (0.42) | ALDH1A1TSHRCES1KCNN4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 570 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755983-B1 | SUBSTITUTED CARBONYLOXYMETHYLPHOSPHORAMIDATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2017-03-15 | — | — | EP | claimed |
| US-9403863-B2 | Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS LLC (US) | 2016-08-02 | — | — | US | claimed |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | claimed |
| EP-1899358-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | Phosphoenix SARL (FR) | 2008-03-19 | — | — | EP | claimed |
| WO-2006136695-A2 | NOVEL P-CHIRAL FUNCTIONALISED ARYLPHOSPHINES AND DERIVATIVES, THE PREPARATION AND USE THEREOF FOR ASYMMETRICAL CATALYSIS | PHOSPHOENIX SARL (FR) | 2006-12-28 | — | — | WO | claimed |
| EP-0906295-B1 | DIBENZO-OXAZEPINE AND -DIOXEPINE DERIVATIVES AND THEIR USE AS ANTI-TUMOR AGENTS | HOFFMANN LA ROCHE (CH) | 2001-10-24 | — | — | EP | claimed |
| EP-0906295-A1 | DIBENZO-OXAZEPINE AND -DIOXEPINE DERIVATIVES AND THEIR USE AS ANTI-TUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-04-07 | — | — | EP | claimed |
| US-5811420-A | SUBSTITUTED 6,7-DIHYDRO-5A-DIBENZO(B,E)(1,4)DIOXAPINE DERIVATIVES; ANTICARCINOGENIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-22 | — | — | US | claimed |
| WO-1997047611-A1 | DIBENZO-OXAZEPINE AND -DIOXEPINE DERIVATIVES AND THEIR USE AS ANTI-TUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-12-18 | — | — | WO | claimed |
| US-5449684-A | Antitumor agents and viricides | PHARMAMAR, S.A. (ES) | 1995-09-12 | — | — | US | claimed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | claimed |
| EP-0098942-B1 | OPTICALLY ACTIVE IMIDAZOLYLPROPANOL COMPOUNDS, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-03-12 | — | — | EP | claimed |
| JP-11246532-A | — | — | None | — | — | JP | disclosed |
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-11970432-B2 | Process for preparing 2-methyl-N-(2′-methylbutyl)butanamide | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-04-30 | — | — | US | disclosed |
| US-20240101562-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESISTANT CANCER, COMPRISING SAME | HOLOSMEDIC (KR) | 2024-03-28 | — | — | US | disclosed |
| WO-1985005622-A1 | 1,24-DIHYDROXY-DELTA22-VITAMIN D3 AND PROCESS FOR PREPARING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-12-19 | — | — | WO | disclosed |
| EP-0119251-A1 | HYDROXYVITAMIN D 2? COMPOUNDS AND PROCESS FOR PREPARING THEM | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4448721-A | Hydroxyvitamin D2 compounds and process for preparing same | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1984-05-15 | — | — | US | disclosed |
| WO-1984001155-A1 | HYDROXYVITAMIN D2 COMPOUNDS AND PROCESS FOR PREPARING THEM | WISCONSIN ALUMNI RES FOUND (US) | 1984-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11970432-B2 | Process for preparing 2-methyl-N-(2′-methylbutyl)butanamide | ALKBH5, ALKBH2, ADRB2 | ALDH1A1 560/4885TSHR 2615/4885CES1 1774/4885 |
| US-20240101562-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESISTANT CANCER, COMPRISING SAME | SLC11A2, ABCC1, TSG101 | ALDH1A1 3381/4885TSHR 4766/4885CES1 1602/4885 |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | ALDH1A1 834/4885TSHR 3165/4885CES1 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.