Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.30 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.30 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015734 | 0.74 | ADORA2A (0.37) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL221825 | 0.74 | SLC9A1 (0.41) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL1535111 | 0.74 | GAA (0.38) | GAAERCC1ERCC4 | |
| SCHEMBL9118456 | 0.74 | PDE4A (0.44) | GAAADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6561465 | 0.73 | — | — | |
| SCHEMBL2078821 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9685966 | 0.73 | ALDH1A1 (0.37) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL11480635 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL16652006 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL25979874 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999274-A2 | METHODS AND SYSTEMS FOR EVALUATING HEALTH RISK FACTORS BY MEASUREMENT OF DNA DAMAGE AND DNA REPAIR | Laboratory Corporation of America Holdings (US) | 2008-12-10 | — | — | EP | claimed |
| US-20070269824-A1 | Methods and systems for evaluating health risk factors by measurement of DNA damage and DNA repair | ALBRECHT JEFFREY | 2007-11-22 | — | — | US | claimed |
| WO-2007103116-A2 | METHODS AND SYSTEMS FOR EVALUATING HEALTH RISK FACTORS BY MEASUREMENT OF DNA DAMAGE AND DNA REPAIR | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2007-09-13 | — | — | WO | claimed |
| EP-0898575-B1 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT DR (US) | 2004-12-29 | — | — | EP | claimed |
| CN-119677866-A | Substrate cleavage for nucleic acid synthesis | 特韦斯特生物科学公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-111868260-B | Methods and materials for assessing and treating cancer | 约翰斯霍普金斯大学 | 2025-02-21 | — | — | CN | disclosed |
| CN-118382631-A | MAGEC2 immunogenic peptides, binding proteins recognizing MAGEC2 immunogenic peptides and uses thereof | 帝斯肯医疗公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-117164683-A | Mutant CSGG wells | 弗拉芒区生物技术研究所 | 2023-12-05 | — | — | CN | disclosed |
| EP-3983546-A1 | ANTISENSE RNA EDITING OLIGONUCLEOTIDES COMPRISING CYTIDINE ANALOGS | ProQR Therapeutics II B.V. (NL) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020252376-A1 | ANTISENSE RNA EDITING OLIGONUCLEOTIDES COMPRISING CYTIDINE ANALOGS | PROQR THERAPEUTICS II B.V. (NL) | 2020-12-17 | — | — | WO | disclosed |
| EP-3283502-A1 | METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME | THE GENERAL HOSPITAL CORPORATION (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016164463-A1 | METHODS FOR REACTIVATING GENES ON THE INACTIVE X CHROMOSOME | THE GENERAL HOSPITAL CORPORATION (US) | 2016-10-13 | — | — | WO | disclosed |
| EP-1999274-A2 | METHODS AND SYSTEMS FOR EVALUATING HEALTH RISK FACTORS BY MEASUREMENT OF DNA DAMAGE AND DNA REPAIR | Laboratory Corporation of America Holdings (US) | 2008-12-10 | — | — | EP | disclosed |
| US-20070269824-A1 | Methods and systems for evaluating health risk factors by measurement of DNA damage and DNA repair | ALBRECHT JEFFREY | 2007-11-22 | — | — | US | disclosed |
| WO-2007103116-A2 | METHODS AND SYSTEMS FOR EVALUATING HEALTH RISK FACTORS BY MEASUREMENT OF DNA DAMAGE AND DNA REPAIR | LABORATORY CORPORATION OF AMERICA HOLDINGS (US) | 2007-09-13 | — | — | WO | disclosed |
| EP-0497609-B1 | Pyrimido-benzothiazine derivatives for the treatment of inflammation, allergy and cardiovascular disease | PFIZER (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0497609-A1 | Pyrimido-benzothiazine derivatives for the treatment of inflammation, allergy and cardiovascular disease | PFIZER INC. (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0006987-A1 | 2,4-Diamino-5-benzylpyrimidines, especially for the treatment of microbial infections, pharmaceutical compositions containing these compounds and processes for preparing these compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1980-01-23 | — | — | EP | disclosed |