SCHEMBL466059

SCHEMBL466059

CCCCCCCCCCCCCCOCC(C)OC(C)=O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.52
PLA2G2C Q5R387 7/20 0.51
USP2 O75604 1/20 0.49
ADRA1D P25100 1/20 0.48
PTAFR P25105 1/20 0.48
HTR1D P28221 1/20 0.48
HTR2C P28335 1/20 0.48
ADRA1B P35368 1/20 0.48
DRD3 P35462 1/20 0.48
TMEM97 Q5BJF2 1/20 0.48
SPHK1 Q9NYA1 1/20 0.47
HTT P42858 1/20 0.47
LPAR5 Q9H1C0 1/20 0.45
LPAR1 Q92633 1/20 0.44
LPAR3 Q9UBY5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL896030 1.00 CES2 (0.52) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL6881438 1.00 CES2 (0.52) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL2230535 0.98 PLA2G2C (0.49) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL896773 0.94 PLA2G2C (0.47) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL896910 0.94 PLA2G2C (0.47) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL107643 0.93 ALDH1A1 (0.47) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL6531007 0.92 TDP1 (0.46) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL19064961 0.92 TDP1 (0.46) CES2PLA2G2CUSP2ADRA1DPTAFR
Water SCHEMBL27447449 0.91 ALDH1A1 (0.45) CES2PLA2G2CUSP2ADRA1DPTAFR
SCHEMBL27550833 0.91 LMNA (0.54) PLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281376-A1 Hair Care Composition CORET JOEL MARCEL (US) 2025-09-11 US claimed
US-20250269034-A1 TOPICAL TETRACYCLINE COMPOSITIONS JOURNEY MEDICAL CORP (US) 2025-08-28 US claimed
CN-118948631-B Oil-in-water cleansing composition 深圳市护家科技有限公司 2025-02-14 CN claimed
CN-118948631-A Oil-in-water cleansing composition 深圳市护家科技有限公司 2024-11-15 CN claimed
US-12138311-B2 Topical tetracycline compositions JOURNEY MEDICAL CORPORATION (US) 2024-11-12 US claimed
CN-116370328-A Skin care composition and external skin preparation 深圳市护家科技有限公司 2023-07-04 CN claimed
US-10946101-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses VYNE THERAPEUTICS INC. (US) 2021-03-16 US claimed
US-20210015927-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES SWK FUNDING LLC 2021-01-21 US claimed
US-20200261586-A1 TOPICAL TETRACYCLINE COMPOSITIONS FOAMIX PHARMACEUTICALS LTD. (IL) 2020-08-20 US claimed
US-20190134204-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES SWK FUNDING LLC 2019-05-09 US claimed
WO-2011039637-A2 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES FOAMIX LTD. (IL) 2011-04-07 WO claimed
WO-2011039638-A2 TOPICAL TETRACYCLINE COMPOSITIONS FOAMIX LTD. (IL) 2011-04-07 WO claimed
EP-2025058-A2 COMPOSITIONS AND METHODS TO TREAT SKIN DISEASES CHARACTERIZED BY CELLULAR PROLIFERATION AND ANGIOGENESIS Paloma Pharmaceuticals, Inc. (US) 2009-02-18 EP claimed
US-20080233067-A1 Method Of Making Enhanced Efficacy Antiperspirant Actives COLGATE-PALMOLIVE COMPANY (US) 2008-09-25 US claimed
WO-2007133249-A2 COMPOSITIONS AND METHODS TO TREAT SKIN DISEASES CHARACTERIZED BY CELLULAR PROLIFERATION AND ANGIOGENESIS PALOMA PHARMACEUTICALS, INC. (US) 2007-11-22 WO claimed
US-20060257337-A1 Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis PALOMA PHARMACEUTICALS, INC. 2006-11-16 US claimed
WO-2006062926-A1 METHODS FOR PREPARING SKIN FOR BIOMETRIC IMAGE ACQUISITION APRILIS, INC. (US) 2006-06-15 WO claimed
US-20040185018-A1 Nail enamelcompositions and methods CITICORP USA, INC. 2004-09-23 US claimed
US-5516506-A LOTIONS WITH GLYCERINE, MAGNESIUM ALUMINUM SILICATE, XANTHAN GUM, ISOSTEARIC ACID, SILICONES, OCTYL METHOXY CINNAMATE AND EMOLLIENTS AND ESTER COMPOUNDS BERNEL CHEMICAL CO. (US) 1996-05-14 US claimed
US-5008100-A Stable sunscreens ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1991-04-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040185018-A1 Nail enamelcompositions and methods ETF1, POLR1C, PIK3C3 CES2 1007/4885PLA2G2C 3788/4885USP2 1228/4885
US-20060257337-A1 Compositions and methods to treat skin diseases characterized by cellular proliferation and angiogenesis MKI67, VEGFA, TYR CES2 4342/4885PLA2G2C 4236/4885USP2 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.