Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504884 | 0.81 | FAAH (0.44) | FAAHGAAL3MBTL1HPGDHSD17B10 | |
| SCHEMBL30890827 | 0.75 | FAAH (0.46) | FAAHGAAL3MBTL1HPGDHSD17B10 | |
| SCHEMBL8507123 | 0.75 | HPGD (0.67) | L3MBTL1HPGDHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL11089043 | 0.74 | HPGD (0.51) | GAAL3MBTL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL17773307 | 0.74 | RAB9A (0.47) | FAAHL3MBTL1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6695897 | 0.74 | NPC1 (0.51) | GAAL3MBTL1HPGDHSD17B10RAB9A | |
| SCHEMBL30890579 | 0.74 | HPGD (0.65) | GAAHPGDHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL3416627 | 0.73 | RIPK1 (0.52) | L3MBTL1HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7801637 | 0.73 | ALDH1A1 (0.55) | L3MBTL1HPGDHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL6698851 | 0.73 | NPC1 (0.50) | GAAL3MBTL1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924561-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | Eli Lilly & Company (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007028083-A2 | 6-ARYLALKYLAMINO- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |