SCHEMBL4666295

SCHEMBL4666295

OB(O)c1cccc(-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.37
ALDH1A1 P00352 3/20 0.37
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 3/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.34
ENPP2 Q13822 2/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
PLG P00747 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3256000 0.85 CA1 (0.43) MGLLL3MBTL1ALDH1A1POLBTSHR
SCHEMBL976147 0.81 LMNA (0.47) L3MBTL1ALDH1A1POLBKMT2ATSHR
SCHEMBL7611179 0.80 MAOA (0.43) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL9057649 0.76 KCNJ1 (0.42) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL8698703 0.74 AGTR1 (0.47) L3MBTL1ALDH1A1POLBKMT2ATSHR
SCHEMBL654077 0.74 AGTR1 (0.39) ALDH1A1POLBMEN1KMT2ATSHR
SCHEMBL9235857 0.73 MEN1 (0.42) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL3218252 0.72 CYP11B1 (0.33) ALDH1A1TSHRMAPTNPSR1ENPP2
SCHEMBL9447398 0.72 AGTR1 (0.36) L3MBTL1ALDH1A1POLBMEN1KMT2A
SCHEMBL29931122 0.72 AGTR1 (0.44) MGLLALDH1A1POLBHSD11B1AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1931648-A2 PROCESSES FOR THE SYNTHESIS OF 5-PHENYL -1 TRITYL-1H-TETRAZOLE Teva Pharmaceutical Industries Ltd. (IL) 2008-06-18 EP disclosed
WO-2008027385-A2 PROCESSES FOR THE SYNTHESIS OF 5-PHENYL -1 TRITYL-1H-TETRAZOLE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2008-03-06 WO disclosed