Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | AGT | P01019 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357842 | 0.83 | ALDH1A1 (0.42) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9235857 | 0.80 | MEN1 (0.42) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL976147 | 0.79 | LMNA (0.47) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9025603 | 0.79 | MEN1 (0.41) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9025749 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2447241 | 0.76 | KCNN4 (0.43) | AGTR1AGTR2ALDH1A1TSHRMEN1 | |
| SCHEMBL7611179 | 0.75 | MAOA (0.43) | ALDH1A1TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL7196989 | 0.75 | AGTR1 (0.41) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7393388 | 0.74 | AGTR1 (0.44) | AGTR1AGTR2TP53AGTMAPT | |
| SCHEMBL3838617 | 0.74 | AGTR1 (0.41) | AGTR1AGTR2ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274104-A | N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders | ELF SANOFI, A FRENCH CORP. (FR) | 1993-12-28 | — | — | US | disclosed |