Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA3 | P07451 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL25326318 | 1.00 | CA12 (0.58) | CA12CA1CA2CA9CA3 | |
| Trifluoroacetic Acid SCHEMBL5776611 | 1.00 | CA12 (0.58) | CA12CA1CA2CA9CA3 | |
| Trifluoroacetic Acid SCHEMBL30260008 | 1.00 | CA12 (0.58) | CA12CA1CA2CA9CA3 | |
| Hydroquinone SCHEMBL27638163 | 0.89 | CA2 (0.50) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL27815365 | 0.87 | CA12 (0.55) | CA12CA1CA2CA9CA3 | |
| Phenol SCHEMBL81020 | 0.87 | CA12 (0.55) | CA12CA1CA2CA9CA3 | |
| Trifluoroacetic Acid SCHEMBL5571447 | 0.87 | CA12 (0.44) | CA12CA1CA2CA9CA3 | |
| Resorcinol SCHEMBL11567030 | 0.85 | ALDH1A1 (0.57) | CA12CA1CA2CA9CA14 | |
| Trifluoroacetamide SCHEMBL2766693 | 0.85 | TDP1 (0.52) | CA12CA1CA2CA9CA3 | |
| Catechol SCHEMBL9330300 | 0.84 | CA2 (0.53) | CA12CA1CA2CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056730-B | A kind of synthetic method and its application of bupropion hydrochloride sustained release tablets impurity isomers | 浙江普洛家园药业有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-107056730-A | A kind of synthetic method of bupropion hydrochloride sustained release tablets impurity isomers and its application | 浙江普洛家园药业有限公司 | 2017-08-18 | — | — | CN | claimed |
| US-7459550-B2 | Process for the preparation of Cefditoren | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2008-12-02 | — | — | US | claimed |
| CN-100343259-C | Process for the preparation of 3-propenyl cephalosporin DMF solvate | ORCHID CHEMICALS & PHARM LTD (IN) | 2007-10-17 | — | — | CN | claimed |
| CN-1856461-A | Cycloalkylene compounds as estrogen receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2006-11-01 | — | — | CN | claimed |
| EP-1562957-B1 | PROCESS FOR THE PREPARATION OF 3-PROPENYL CEPHALOSPORIN DMF SOLVATE | ORCHID CHEMICALS & PHARM LTD (IN) | 2006-09-13 | — | — | EP | claimed |
| US-20060173175-A1 | Process for the preparation of cefditoren | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2006-08-03 | — | — | US | claimed |
| CN-1694888-A | Process for the preparation of 3-propenyl cephalosporin DMF solvate | ORCHID CHEMICALS & PHARM LTD (IN) | 2005-11-09 | — | — | CN | claimed |
| EP-1562957-A1 | PROCESS FOR THE PREPARATION OF 3-PROPENYL CEPHALOSPORIN DMF SOLVATE | Orchid Chemicals and Pharmaceuticals Ltd (IN) | 2005-08-17 | — | — | EP | claimed |
| US-6903211-B2 | Process for the preparation of 3-propenyl cephalosporin DMF solvate | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2005-06-07 | — | — | US | claimed |
| EP-1501839-A2 | PROCESS FOR THE PREPARATION OF CEFTIOFUR ACID | Orchid Chemicals & Pharmaceuticals Ltd. (IN) | 2005-02-02 | — | — | EP | claimed |
| WO-2005003141-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFDITOREN | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2005-01-13 | — | — | WO | claimed |
| US-6800756-B2 | CONDENSATION; CYCLIZATION | ORCHID CHEMICALS AND PHARMACEUTICALS, LTD. (IN) | 2004-10-05 | — | — | US | claimed |
| WO-2004083216-A1 | A PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-09-30 | — | — | WO | claimed |
| US-20040132995-A1 | Process for the preparation of cephalosporins | ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2004-07-08 | — | — | US | claimed |
| WO-2004039812-A1 | PROCESS FOR THE PREPARATION OF 3-PROPENYL CEPHALOSPORIN DMF SOLVATE | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-13 | — | — | WO | claimed |
| US-20040087786-A1 | Process for the preparation of 3-propenyl cephalosporin DMF solvate | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-06 | — | — | US | claimed |
| WO-2004005295-A1 | NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | claimed |
| US-20030216567-A1 | New method for the preparation of ceftiofur sodium and its intermediates | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2003-11-20 | — | — | US | claimed |
| WO-2003093278-A2 | PROCESS FOR THE PREPARATION OF CEFTIOFUR ACID | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2003-11-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087786-A1 | Process for the preparation of 3-propenyl cephalosporin DMF solvate | CYP2F1, PEF1, CYP4Z1 | CA12 3018/4885CA1 2411/4885CA2 3170/4885 |
| US-20030216567-A1 | New method for the preparation of ceftiofur sodium and its intermediates | BLVRB, CBR1, DCXR | CA12 1510/4885CA1 2801/4885CA2 482/4885 |
| US-20060173175-A1 | Process for the preparation of cefditoren | DHPS, FDPS, CYP4F2 | CA12 2125/4885CA1 2475/4885CA2 2643/4885 |
| US-20040132995-A1 | Process for the preparation of cephalosporins | CYP2F1, CYP7A1, MRPL21 | CA12 2377/4885CA1 3801/4885CA2 3291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.