Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596896 | 0.95 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL6800482 | 0.79 | LMNA (0.47) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL4667729 | 0.78 | CA2 (0.89) | CA2CA1CA9HTTCA12 | |
| SCHEMBL11266395 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL7046052 | 0.78 | CA2 (0.59) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL14596895 | 0.76 | ALDH1A1 (0.60) | SMN1; SMN2LMNACA2ALDH1A1HTT | |
| SCHEMBL11704991 | 0.75 | CA1 (0.67) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL8690274 | 0.75 | CA1 (0.67) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL866410 | 0.75 | CA1 (0.71) | SMN1; SMN2LMNACA2CA1CA9 | |
| SCHEMBL28498472 | 0.74 | CA1 (0.65) | CA2CA1CA9ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |