Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707580 | 0.68 | — | — | |
| Urea SCHEMBL5045628 | 0.65 | L3MBTL1 (0.44) | NPC1 | |
| SCHEMBL4704460 | 0.64 | — | — | |
| Carbamic Acid SCHEMBL29704037 | 0.62 | ACHE (0.44) | NPC1 | |
| SCHEMBL3375870 | 0.61 | L3MBTL1 (0.41) | NPC1 | |
| Carbamic Acid SCHEMBL2830897 | 0.60 | ACHE (0.47) | NPC1 | |
| Hydrochloric Acid SCHEMBL14844794 | 0.55 | NOS3 (0.48) | — | |
| SCHEMBL23963672 | 0.53 | ALDH1A1 (0.55) | — | |
| SCHEMBL7749269 | 0.53 | ALDH1A1 (0.55) | — | |
| SCHEMBL14511334 | 0.53 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907365-A1 | SALTS OF SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | Laboratorios del Dr. Esteve S.A. (ES) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007009708-A1 | SALTS OF SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-25 | — | — | WO | disclosed |