Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL5045628 | 0.88 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1F2CA2CA1 | |
| Carbamic Acid SCHEMBL29704037 | 0.85 | ACHE (0.44) | L3MBTL1ALDH1A1F2CA2CA1 | |
| Hydrochloric Acid SCHEMBL18241090 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HSD11B1CA2HPGDMMP1 | |
| Carbamic Acid SCHEMBL2830897 | 0.81 | ACHE (0.47) | L3MBTL1ALDH1A1F2CA2CA1 | |
| Cyclohexane SCHEMBL10908944 | 0.80 | LMNA (0.42) | L3MBTL1ALDH1A1CA2HPGD | |
| Urea SCHEMBL26980850 | 0.78 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1F2CA2CA1 | |
| SCHEMBL3658220 | 0.73 | MGLL (0.40) | ALDH1A1F2CA2CA1POLB | |
| SCHEMBL2807354 | 0.73 | MGLL (0.40) | ALDH1A1F2CA2CA1POLB | |
| SCHEMBL6926105 | 0.73 | MGLL (0.40) | ALDH1A1F2CA2CA1POLB | |
| SCHEMBL2457046 | 0.73 | MGLL (0.40) | ALDH1A1F2CA2CA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101005840-A | Process for preparing camptothecin derivatives, novel intermediates and compounds thereof | CHATHAM BIOTEC LTD (CA) | 2007-07-25 | — | — | CN | claimed |
| EP-1995249-B1 | CAMPTOTHECIN DERIVATIVES AND THEIR USE | SHANGHAI INST MATERIA MEDICA (CN) | 2010-11-10 | — | — | EP | disclosed |
| US-20090325996-A1 | CAMPTOTHECIN DERIVATIVES AND THEIR USE | SHANGHAI HAIHE PHARMACEUTICAL CO., LTD. (CN) | 2009-12-31 | — | — | US | disclosed |
| EP-1995249-A1 | CAMPTOTHECIN DERIVATIVES AND THEIR USE | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2008-11-26 | — | — | EP | disclosed |
| CN-101005840-A | Process for preparing camptothecin derivatives, novel intermediates and compounds thereof | CHATHAM BIOTEC LTD (CA) | 2007-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325996-A1 | CAMPTOTHECIN DERIVATIVES AND THEIR USE | TOP2A, TOP1, TOP2B | L3MBTL1 4660/4885ALDH1A1 1564/4885F2 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.