Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040847 | 0.85 | HDAC1 (0.57) | MAPTPOLBNPC1RAB9ACA1 | |
| SCHEMBL8966015 | 0.84 | NPC1 (0.54) | MAPTPOLBNPC1RAB9ACA1 | |
| Hydrochloric Acid SCHEMBL11734939 | 0.83 | HDAC1 (0.56) | MAPTPOLBNPC1RAB9ACA1 | |
| SCHEMBL4669202 | 0.82 | MAPT (0.47) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL628743 | 0.82 | NPC1 (0.66) | MAPTPOLBNPC1RAB9ACA1 | |
| SCHEMBL4667391 | 0.82 | MAPT (0.52) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7251385 | 0.81 | GAA (0.54) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4669153 | 0.81 | ALDH1A1 (0.50) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL115706 | 0.81 | CA1 (0.63) | MAPTPOLBNPC1RAB9ACA1 | |
| SCHEMBL1358811 | 0.81 | MAPT (0.63) | MAPTPOLBNPC1RAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | disclosed |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | disclosed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |
| US-6635091-B2 | Oxidation color dye and coupler | L'OREAL S. A. (FR) | 2003-10-21 | — | — | US | disclosed |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | L'OREAL SA (FR) | 2002-12-05 | — | — | US | disclosed |
| EP-1175198-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2002-01-30 | — | — | EP | disclosed |
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1129689-A2 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |
| WO-2001062220-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES COMPRISING A N-(2-HYDROBENZENE)-CARBAMATE OR A N-(2-HYDROXY-BENZENE)-UREA AND A PYRAZOLOPYRIMINE, DYEING METHODS | L'OREAL (FR) | 2001-08-30 | — | — | WO | disclosed |
| US-6132943-A | A MULTILAYER SILVER HALIDE COLOR PHOTOGRAPHIC FILM HAVING COLORED MASKING COUPLERS FOR CORRECTING THE UNWANTED YELLOW SIDE ABSORPTION OF MAGENTA DYE-FORMING COUPLERS | EASTMAN KODAK COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-3934017-A | Anthelmintic composition and method utilizing isothiocyanobenzazoles active ingredients | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034914-A1 | Compositions for the oxidation dyeing of keratinous fibers comprising at least one coupler, and dyeing methods | KRT18, FH, FGB | MAPT 563/4885POLB 60/4885NPC1 4448/4885 |
| US-20020178512-A1 | Oxidation dyeing composition for keratinous fibres comprising a n-(2-hydrobenzene)-carbamate or a n-(2-hydroxy-benzene)-urea and a pyrazolopyrimine, dyeing methods | FH, KRT18, CYB5R3 | MAPT 879/4885POLB 123/4885NPC1 4742/4885 |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | MAPT 664/4885POLB 1655/4885NPC1 4534/4885 |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | MAPT 664/4885POLB 1655/4885NPC1 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.