SCHEMBL467101

SCHEMBL467101

[c]1ccccc1-c1ccc2ccccc2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.47
NPC1 O15118 10/20 0.47
CYP1A2 P05177 3/20 0.47
CYP3A4 P08684 3/20 0.47
AR P10275 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 9/20 0.44
KDM4E B2RXH2 9/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
HSD17B10 Q99714 4/20 0.44
PKM P14618 4/20 0.44
HPGD P15428 4/20 0.44
TP53 P04637 3/20 0.44
MAPT P10636 3/20 0.44
PMP22 Q01453 2/20 0.44
HCRTR1 O43613 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370752 0.79 TGFBR1 (0.43) RAB9ANPC1CYP1A2CYP3A4ALDH1A1
SCHEMBL29374931 0.76 RAB9A (0.64) RAB9ANPC1CYP1A2CYP3A4AR
SCHEMBL170196 0.76 RAB9A (0.64) RAB9ANPC1CYP1A2CYP3A4AR
SCHEMBL1327331 0.76 RAB9A (0.50) RAB9ANPC1CYP1A2CYP3A4AR
SCHEMBL713066 0.76 NPC1 (0.47) RAB9ANPC1CYP1A2MEN1KMT2A
SCHEMBL713792 0.75 ALDH1A1 (0.41) CYP3A4CYP2D6MEN1KMT2AALDH1A1
SCHEMBL3146084 0.74 KDM4E (0.41) RAB9ANPC1CYP1A2KMT2AALDH1A1
SCHEMBL3889478 0.74 RAB9A (0.41) RAB9ANPC1CYP1A2CYP3A4AR
SCHEMBL715296 0.74 LMNA (0.52) CYP3A4CYP2D6MEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL31243061 0.74 ALDH1A1 (0.63) RAB9ANPC1CYP1A2CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263912-A Azanaphthyl substituted electricity-absorbing fragment compound and application thereof 烟台显华科技集团股份有限公司 2023-12-22 CN claimed
US-20230220161-A1 POLYIMIDE PRECURSOR PREPARED BY USING POLYCYCLIC MONOMER INCLUDING TRIFLUOROMETHYL GROUP AND FLEXIBLE POLYIMIDE OBTAINED BY USING THE SAME KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-07-13 US claimed
CN-110540527-B Novel triphenylene compound and organic light-emitting device using same 株式会社LG化学 2023-04-07 CN claimed
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN claimed
CN-111316459-A Photoelectric conversion element and imaging device 索尼公司 2020-06-19 CN claimed
US-10566548-B2 Image sensor, stacked imaging device and imaging module SONY CORPORATION (JP) 2020-02-18 US claimed
EP-3300114-B1 IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE SONY CORP (JP) 2020-01-08 EP claimed
CN-110540527-A Novel triphenylene compound and organic light-emitting device using same LG CHEMICAL LTD 2019-12-06 CN claimed
US-20180114926-A1 IMAGE SENSOR, STACKED IMAGING DEVICE AND IMAGING MODULE SONY CORPORATION (JP) 2018-04-26 US claimed
EP-3300114-A1 IMAGING ELEMENT, MULTILAYER IMAGING ELEMENT AND IMAGING DEVICE Sony Corporation (JP) 2018-03-28 EP claimed
JP-2007501804-A 2007-02-01 JP claimed
EP-1673357-A2 HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2006-06-28 EP claimed
US-20060025415-A1 Compositions useful as inhibitors of voltage-gated sodium channels VERTEX PHARMACEUTICALS INCORPORATED 2006-02-02 US claimed
US-20050137190-A1 Compositions useful as inhibitors of voltage-gated sodium channels VERTEX PHARMACEUTICALS INCORPORATED 2005-06-23 US claimed
WO-2005013914-A2 HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2005-02-17 WO claimed
EP-0770079-B1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO (JP) 2003-02-12 EP claimed
US-20020107251-A1 Heterobicyclic derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-08-08 US claimed
US-6426345-B1 PHOSPHODIESTERASE INHIBITORS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-07-30 US claimed
EP-0770079-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-05-02 EP claimed
WO-1996001825-A1 HETEROBICYCLIC DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-01-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050137190-A1 Compositions useful as inhibitors of voltage-gated sodium channels SCNN1G, KCNN3, KCNN2 RAB9A 1749/4885NPC1 487/4885CYP1A2 4265/4885
US-20060025415-A1 Compositions useful as inhibitors of voltage-gated sodium channels SCNN1G, KCNN3, KCNN2 RAB9A 1749/4885NPC1 487/4885CYP1A2 4265/4885
US-20020107251-A1 Heterobicyclic derivatives ARSA, ARRB1, SULT2A1 RAB9A 1092/4885NPC1 875/4885CYP1A2 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.