Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.39 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670479 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPK1ATMMEN1KMT2A | |
| SCHEMBL4670427 | 0.82 | ADORA2B (0.41) | ALDH1A1ADORA2AADORA2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9384727 | 0.81 | ADORA2B (0.40) | ALDH1A1ADORA2AADORA2BMEN1KMT2A | |
| SCHEMBL4672091 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1ATMMEN1KMT2A | |
| SCHEMBL4673352 | 0.79 | MAPK1 (0.50) | ALDH1A1MAPK1ATMMEN1KMT2A | |
| SCHEMBL4670468 | 0.79 | PARP15 (0.42) | ALDH1A1MAPK1ATMMEN1KMT2A | |
| SCHEMBL4670421 | 0.79 | PARP10 (0.42) | ALDH1A1MAPK1ATMMEN1KMT2A | |
| SCHEMBL4677832 | 0.78 | PARP15 (0.43) | MAPK1ATMMEN1KMT2ATSHR | |
| SCHEMBL4670081 | 0.78 | ADRB2 (0.42) | ALDH1A1MAPK1ATMTSHRNPC1 | |
| SCHEMBL4673552 | 0.78 | MAPK1 (0.49) | ALDH1A1MAPK1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |
| US-6051586-A | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | BAYER CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |