Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673554 | 0.85 | KMT2A (0.47) | MAPK1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4673352 | 0.80 | MAPK1 (0.50) | MAPK1ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL4670084 | 0.79 | ROCK2 (0.56) | MAPK1ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL4676105 | 0.79 | PKM (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4675102 | 0.78 | ALDH1A1 (0.42) | MAPK1ATMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4670479 | 0.73 | ALDH1A1 (0.39) | MAPK1ATMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4670468 | 0.72 | PARP15 (0.42) | MAPK1ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL4670421 | 0.72 | PARP10 (0.42) | MAPK1ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL4675910 | 0.72 | PARP10 (0.39) | MAPK1ATMKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4670081 | 0.71 | ADRB2 (0.42) | MAPK1ATMALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |