Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.51 |
| ▸ | MMP8 | P22894 | 6/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.38 |
| ▸ | NPY4R | P50391 | 3/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679584 | 0.84 | MMP2 (0.51) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL4683795 | 0.84 | MMP2 (0.51) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL4677415 | 0.83 | KISS1R (0.45) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL4677382 | 0.83 | KISS1R (0.45) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL5557511 | 0.73 | MMP2 (0.54) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL760986 | 0.73 | MMP2 (0.60) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL5556628 | 0.70 | CTSS (0.76) | MMP9MMP8MMP2CTSLCTSS | |
| SCHEMBL8360546 | 0.69 | MMP2 (0.53) | MMP9MMP8MMP2MMP1MMP3 | |
| SCHEMBL5552080 | 0.69 | MMP2 (0.83) | MMP9MMP8MMP2MMP1MMP3 | |
| SCHEMBL5552074 | 0.69 | MMP2 (0.83) | MMP9MMP8MMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633702-B1 | PROTEASE INHIBITORS | PROZYMEX AS (DK) | 2008-07-02 | — | — | EP | disclosed |