Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | MMP7 | P09237 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242111 | 0.93 | PTPN1 (0.50) | MMP2MMP9MMP8PTPN1MMP1 | |
| SCHEMBL8363817 | 0.83 | MMP2 (0.62) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL6846292 | 0.81 | FAAH (0.54) | MMP2MMP9MMP8 | |
| SCHEMBL8236030 | 0.81 | FAAH (0.54) | MMP2MMP9MMP8 | |
| SCHEMBL14177783 | 0.81 | CCKBR (0.61) | MMP2MMP9MMP8PTPN1MMP1 | |
| SCHEMBL8363816 | 0.79 | MMP8 (0.58) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL8360545 | 0.78 | MMP2 (0.55) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL14177510 | 0.77 | CCKBR (0.61) | MMP2MMP9MMP8PTPN1MMP1 | |
| SCHEMBL8241705 | 0.77 | MEN1 (0.51) | — | |
| SCHEMBL8360549 | 0.77 | MMP2 (0.56) | MMP2MMP9MMP8MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932853-A1 | Novel depsipeptides and process for preparing same | Cubist Pharmaceutical Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2003014147-A1 | NOVEL DEPSIPEPTIDES AND PROCESS FOR PREPARING SAME | CUBIST PHARMACEUTICALS, INC. (US) | 2003-02-20 | — | — | WO | disclosed |