Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688192 | 0.90 | L3MBTL1 (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL5583648 | 0.90 | BCHE (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL4140684 | 0.90 | ABCB1 (0.53) | L3MBTL1MAPTMAPK1TDP1HTT | |
| SCHEMBL16740415 | 0.84 | MAOA (0.39) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL16356781 | 0.84 | L3MBTL1 (0.65) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL6197763 | 0.84 | PTPN1 (0.65) | L3MBTL1MAPTMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL4149747 | 0.81 | LMNA (0.48) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL31517959 | 0.81 | L3MBTL1 (0.51) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL9682836 | 0.81 | LMNA (0.45) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL9176447 | 0.81 | PTGER1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | BTG INTERNATIONAL LIMITED | 2008-08-21 | — | — | US | disclosed |
| WO-2006103463-A1 | IRON MODULATORS | BTG INTERNATIONAL LIMITED (GB) | 2006-10-05 | — | — | WO | disclosed |
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0336369-A1 | 3-Acylamino-1-[[[(substituted sulfonyl)amino]carbonyl]amino]2-azetidinones | E.R. Squibb & Sons, Inc. (US) | 1989-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200520-A1 | Iron Modulators | SLC40A1, HAMP, FTH1 | L3MBTL1 793/4885MAPT 109/4885MAPK1 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.