Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | METAP2 | P50579 | 5/20 | 0.47 |
| ▸ | METAP1 | P53582 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20299899 | 0.85 | RXRA (0.49) | RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL3857282 | 0.85 | ALOX5 (0.51) | RECQLMETAP2METAP1MAPTGAA | |
| SCHEMBL28724159 | 0.82 | ALDH1A1 (0.42) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1117020 | 0.82 | CA1 (0.52) | GAAALDH1A1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28314990 | 0.82 | ADRA2C (0.53) | RECQLMETAP2METAP1MAPTGAA | |
| SCHEMBL27865576 | 0.81 | RECQL (0.50) | RECQLMAPTGAAALDH1A1MEN1 | |
| SCHEMBL4689285 | 0.81 | MEN1 (0.45) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10337620 | 0.80 | RAB9A (0.55) | RECQLMAPTMEN1KMT2AHPGD | |
| SCHEMBL10851386 | 0.80 | MGAM (0.50) | GAAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11174840 | 0.80 | RNF4 (0.54) | RECQLMETAP2METAP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | QLi5 Therapeutics AG (DE) | 2024-12-19 | — | — | US | claimed |
| CN-108752269-A | A kind of fragrant phenoxy Propionamides compound and its preparation method and application containing chiral carbon | 浙江工业大学 | 2018-11-06 | — | — | CN | claimed |
| EP-1299377-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002000641-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-01-03 | — | — | WO | claimed |
| US-20220024906-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2022-01-27 | — | — | US | disclosed |
| CN-112858493-A | Method for detecting beta-agonists in milk | 内蒙古蒙牛乳业（集团）股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-111802395-A | Fine oxazole glycyrrhiza amine weeding composition containing safener isoxadifen | 江苏中旗科技股份有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-10227330-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2019-03-12 | — | — | US | disclosed |
| CN-108752269-A | A kind of fragrant phenoxy Propionamides compound and its preparation method and application containing chiral carbon | 浙江工业大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-108689921-A | It is a kind of virtue phenoxy base Propionamides compound preparation method with application | 安徽农业大学 | 2018-10-23 | — | — | CN | disclosed |
| US-20180111918-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2018-04-26 | — | — | US | disclosed |
| US-9890138-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | disclosed |
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2013-12-19 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| EP-1299377-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002000641-A2 | SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024906-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | RECQL 161/4885METAP2 3115/4885METAP1 3135/4885 |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | RECQL 1343/4885METAP2 3960/4885METAP1 2338/4885 |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | RECQL 385/4885METAP2 2457/4885METAP1 2779/4885 |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | RECQL 1411/4885METAP2 872/4885METAP1 1362/4885 |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | RECQL 1411/4885METAP2 872/4885METAP1 1362/4885 |
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | PSMB5, PSMA5, PSMB1 | RECQL 1554/4885METAP2 1236/4885METAP1 449/4885 |
| US-20180111918-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | RECQL 1411/4885METAP2 872/4885METAP1 1362/4885 |
| US-10227330-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | HRH2, GIPR, SSTR4 | RECQL 1411/4885METAP2 872/4885METAP1 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.