Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | SLC9A3 | P48764 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469041 | 0.91 | GAA (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL436893 | 0.81 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL21350729 | 0.78 | ALDH1A1 (0.71) | ALDH1A1LMNASMN1; SMN2POLBUSP2 | |
| SCHEMBL17089349 | 0.76 | GAA (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL26154170 | 0.76 | MTNR1A (0.61) | ALDH1A1LMNASMN1; SMN2USP2KMT2A | |
| SCHEMBL31674606 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL19392525 | 0.73 | MEN1 (0.63) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL436861 | 0.73 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL26212915 | 0.72 | LMNA (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2TP53 | |
| SCHEMBL26154133 | 0.72 | L3MBTL1 (0.60) | ALDH1A1SMN1; SMN2USP2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139456-B2 | Chelating compounds and immobilized tethered chelators | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-09-22 | — | — | US | disclosed |
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2012-03-15 | — | — | US | disclosed |
| US-7932326-B2 | Chelating compounds and immobilized tethered chelators | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, TTPA, SLC39A7 | ALDH1A1 3904/4885RORC 3990/4885SLC9A3 2796/4885 |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, SLC30A7, SLC39A7 | ALDH1A1 3115/4885RORC 4097/4885SLC9A3 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.