Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833159 | 0.71 | ALDH1A1 (0.41) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL437174 | 0.70 | TDP1 (0.41) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL6982116 | 0.69 | TDP1 (0.40) | KDM4EMAPTKMT2ALMNAHSD17B10 | |
| Methyl Alcohol SCHEMBL27808930 | 0.66 | HSD17B10 (0.65) | ALDH1A1KMT2AHSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL11451918 | 0.65 | GPR35 (0.50) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL11451916 | 0.65 | GPR35 (0.50) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL17440889 | 0.65 | KMT2A (0.41) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL29930744 | 0.65 | CUL4A (0.43) | CUL4AKDM4EMAPTALDH1A1KMT2A | |
| Acetic Acid SCHEMBL27721273 | 0.65 | HSD17B10 (0.58) | MAPTALDH1A1KMT2AHSD17B10TDP1 | |
| SCHEMBL3253975 | 0.64 | HSD17B10 (0.47) | CUL4AKDM4EMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065239-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA LIMITED (GB) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065239-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | CFH, C5, CFB | CUL4A 3080/4885KDM4E 3115/4885MAPT 4862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.