Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694037 | 0.87 | MALT1 (0.42) | MALT1MAPTTP53MEN1KMT2A | |
| SCHEMBL4689928 | 0.85 | MALT1 (0.47) | MALT1MAPTTP53KMT2AALDH1A1 | |
| SCHEMBL3283289 | 0.84 | CCR5 (0.49) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4693868 | 0.84 | CCR5 (0.48) | MALT1NPC1ALDH1A1HTTL3MBTL1 | |
| SCHEMBL4689933 | 0.81 | MALT1 (0.43) | MALT1MAPTTP53ALDH1A1HTT | |
| SCHEMBL4693286 | 0.79 | TP53 (0.45) | MALT1MAPTTP53KMT2AALDH1A1 | |
| SCHEMBL4694325 | 0.79 | HCRTR1 (0.48) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4692306 | 0.78 | THRB (0.47) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4697499 | 0.78 | P2RX7 (0.49) | — | |
| SCHEMBL3283983 | 0.76 | CCR5 (0.51) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |