Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694230 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL5467919 | 0.85 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL4689474 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AMAPK1LMNA | |
| SCHEMBL4433135 | 0.78 | VCAM1 (0.53) | ALDH1A1KMT2ALMNAHPGDTSHR | |
| SCHEMBL4446049 | 0.78 | VCAM1 (0.53) | ALDH1A1KMT2ALMNAHPGDTSHR | |
| SCHEMBL1069184 | 0.77 | TDP1 (0.53) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL1071311 | 0.77 | KMT2A (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL4689028 | 0.77 | TDP1 (0.44) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL1072166 | 0.76 | HCAR3 (0.46) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 | |
| SCHEMBL1072292 | 0.75 | HCAR3 (0.44) | ALDH1A1SMN1; SMN2MAPTCYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682547-B1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2012-10-24 | — | — | EP | disclosed |
| EP-1682547-A4 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-12-31 | — | — | EP | disclosed |
| US-7323567-B2 | RSV polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2008-01-29 | — | — | US | disclosed |
| EP-1682547-A1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2006-07-26 | — | — | EP | disclosed |
| US-20050239814-A1 | RSV polymerase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2005-10-27 | — | — | US | disclosed |
| WO-2005042530-A1 | RSV POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239814-A1 | RSV polymerase inhibitors | POLR2E, POLR2H, POLR2A | ALDH1A1 1290/4885SMN1; SMN2 199/4885MAPT 3709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.