Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTR1D | P28221 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701662 | 0.81 | PABPC1 (0.52) | MAPTMEN1KMT2AHTTTDP1 | |
| SCHEMBL4700115 | 0.81 | HTR1A (0.45) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL20258596 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL4698600 | 0.79 | GPR84 (0.47) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL4701022 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL4699088 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL8946916 | 0.75 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL31543713 | 0.75 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL6026161 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BMAPTMEN1KMT2A | |
| SCHEMBL18222560 | 0.73 | MTNR1A (0.78) | MTNR1AMTNR1BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |