Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701022 | 0.86 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTSMN1; SMN2HTT | |
| SCHEMBL4697189 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1BMAPTSMN1; SMN2HTT | |
| SCHEMBL4701252 | 0.75 | NPC1 (0.49) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL20258596 | 0.74 | MTNR1A (0.67) | MTNR1AMTNR1BMAPTSMN1; SMN2HTT | |
| SCHEMBL6026161 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BMAPTSMN1; SMN2HTT | |
| SCHEMBL4700115 | 0.73 | HTR1A (0.45) | MTNR1AMTNR1BMAPTSMN1; SMN2LMNA | |
| SCHEMBL6026754 | 0.71 | IDO1 (0.41) | MAPTHTTMEN1KMT2ATDP1 | |
| SCHEMBL4698600 | 0.71 | GPR84 (0.47) | MTNR1AMTNR1BMAPTSMN1; SMN2LMNA | |
| SCHEMBL8946916 | 0.71 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTHTTMEN1 | |
| SCHEMBL31543713 | 0.71 | MTNR1A (1.00) | MTNR1AMTNR1BMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |