Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698600 | 0.89 | GPR84 (0.47) | HTR1AHTR2AFAAHGPR84CDK4 | |
| SCHEMBL4697189 | 0.81 | MTNR1A (0.60) | HTR1AMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL4701662 | 0.73 | PABPC1 (0.52) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL4701022 | 0.73 | MTNR1A (0.49) | HTR2AMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL4699088 | 0.73 | MTNR1A (0.53) | MTNR1AMEN1KMT2AMAPTPOLB | |
| SCHEMBL4697802 | 0.71 | MEN1 (0.53) | HTR1AHTR2AMTNR1AMEN1KMT2A | |
| SCHEMBL4699033 | 0.70 | IDO1 (0.45) | HTR1AHTR2AMTNR1AMEN1KMT2A | |
| SCHEMBL4700117 | 0.70 | HTR1A (0.53) | HTR1AHTR2AGPR84MTNR1ARAB9A | |
| SCHEMBL7976809 | 0.69 | MTNR1A (0.58) | MTNR1AMEN1KMT2AMAPTMTNR1B | |
| SCHEMBL4700989 | 0.68 | IDO1 (0.48) | HTR1AHTR2AMTNR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |