Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.36 |
| ▸ | HTR3B | O95264 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765706 | 0.82 | HTR4 (0.39) | HTR4SIGMAR1MAPTDRD2CYP1A2 | |
| Capeserod SCHEMBL4707724 | 0.81 | HTR4 (0.45) | HTR4SIGMAR1DRD2CYP1A2CYP3A4 | |
| SCHEMBL8364833 | 0.81 | HTR4 (0.46) | HTR4SIGMAR1ACHEDRD2CYP1A2 | |
| Capeserod SCHEMBL399091 | 0.81 | HTR4 (0.44) | HTR4SIGMAR1DRD2DRD3HTR2C | |
| SCHEMBL7804895 | 0.70 | HTR4 (0.42) | HTR4 | |
| SCHEMBL8306432 | 0.65 | HTR4 (0.53) | HTR4SIGMAR1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8364693 | 0.64 | HTR4 (0.52) | HTR4SIGMAR1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8305672 | 0.63 | DRD2 (0.44) | SIGMAR1DRD2DRD4HTR2CCHRM2 | |
| SCHEMBL8320569 | 0.62 | HSD11B1 (0.43) | HTR4SIGMAR1ACHECYP1A2CYP3A4 | |
| SCHEMBL24895553 | 0.61 | CACNA1G (0.55) | SIGMAR1MAPTDRD2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781262-A1 | PHARMACEUTICAL MULTILAYER TABLET FOR CONTROLLED_RELEASE OF ACTIVE INGREDIENTS WITH HIGHLY PH-DEPENDENT SOLUBILITY | Sanofi-Aventis (FR) | 2007-05-09 | — | — | EP | claimed |
| WO-2006010640-A1 | PHARMACEUTICAL MULTILAYER TABLET FOR CONTROLLED RELEASE OF ACTIVE INGREDIENTS WITH HIGHLY PH-DEPENDENT SOLUBILITY | SANOFI-AVENTIS (FR) | 2006-02-02 | — | — | WO | claimed |
| EP-1904037-A1 | PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY | Sanofi-Aventis (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007003746-A1 | PROLONGED RELEASE FORMULATION OF ACTIVE PRINCIPLES HAVING A PH-DEPENDENT SOLUBILITY | SANOFI-AVENTIS (FR) | 2007-01-11 | — | — | WO | disclosed |