Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694023 | 0.85 | P2RX7 (0.47) | P2RX7 | |
| SCHEMBL3283294 | 0.83 | HCRTR1 (0.45) | — | |
| SCHEMBL4694327 | 0.81 | HCRTR1 (0.48) | — | |
| SCHEMBL4693016 | 0.78 | MGLL (0.39) | P2RX7 | |
| SCHEMBL4691180 | 0.77 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL4694036 | 0.77 | HCRTR1 (0.39) | — | |
| SCHEMBL4693869 | 0.76 | CCR5 (0.43) | — | |
| SCHEMBL4692311 | 0.75 | LMNA (0.47) | — | |
| SCHEMBL4697499 | 0.74 | P2RX7 (0.49) | P2RX7 | |
| SCHEMBL3283985 | 0.74 | HCRTR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |