Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417722 | 0.76 | POLB (0.40) | ACEITGB1ITGA5KMT2APOLB | |
| SCHEMBL10362062 | 0.76 | ITGB1 (0.39) | ACEITGB1ITGA5CASP1CASP7 | |
| SCHEMBL6942583 | 0.76 | ITGB1 (0.39) | ACEITGB1ITGA5CASP1CASP7 | |
| SCHEMBL10361083 | 0.76 | ITGB1 (0.39) | ACEITGB1ITGA5CASP1CASP7 | |
| SCHEMBL9197329 | 0.74 | ALDH1A1 (0.33) | ALDH1A1GAAMAPTTHRB | |
| SCHEMBL9194062 | 0.72 | ALDH1A1 (0.31) | ALDH1A1GAAMAPTTHRB | |
| SCHEMBL9079730 | 0.72 | RIPK1 (0.44) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL31742451 | 0.71 | ACE (0.40) | ACEMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL760161 | 0.70 | POLB (0.39) | ITGB1ITGA5POLBMAPT | |
| SCHEMBL2540013 | 0.70 | POLB (0.39) | ITGB1ITGA5POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |