SCHEMBL9197329

SCHEMBL9197329

CCCC[Si](C)(C)N1C(=O)CC1C=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9194062 0.87 ALDH1A1 (0.31) ALDH1A1GAAMAPTTHRB
SCHEMBL4698531 0.74 ACE (0.33) ALDH1A1GAAMAPTTHRB
SCHEMBL9079730 0.71 RIPK1 (0.44) ALDH1A1
SCHEMBL7501306 0.70
SCHEMBL7501312 0.70
SCHEMBL6364235 0.60 MGLL (0.44) ALDH1A1GAAMAPTTHRB
SCHEMBL11474481 0.59 NAAA (0.45) ALDH1A1GAAMAPTTHRB
SCHEMBL12056893 0.56
Hexane SCHEMBL27853777 0.53 CYP1A2 (0.42) ALDH1A1THRB
SCHEMBL3189996 0.52 TSHR (0.38) ALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669912-A1 N-(3-PIPERIDINYLCARBONYL)-BETA-ALANINE DERIVATIVES AS PAF ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-09-06 EP disclosed