Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 6/20 | 0.34 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 5/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701072 | 0.88 | PDCD1 (0.35) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4704896 | 0.88 | CTSK (0.34) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4703639 | 0.86 | CTSK (0.36) | CTSSCTSKCTSLCTSBPRKD1 | |
| SCHEMBL4699572 | 0.86 | CTSL (0.33) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4704688 | 0.82 | CTSL (0.33) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4703317 | 0.82 | HRH3 (0.35) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4703612 | 0.81 | CTSS (0.34) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4703463 | 0.81 | HRH3 (0.37) | KCNH2CTSSCTSKCTSLCTSB | |
| SCHEMBL4701830 | 0.81 | CTSK (0.37) | CTSSCTSKCTSLCTSB | |
| SCHEMBL4699887 | 0.80 | CTSS (0.34) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-10-01 | — | — | EP | disclosed |