Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.37 |
| ▸ | CTSS | P25774 | 9/20 | 0.37 |
| ▸ | CTSL | P07711 | 10/20 | 0.36 |
| ▸ | CTSB | P07858 | 7/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703612 | 0.89 | CTSS (0.34) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4702622 | 0.89 | FYN (0.33) | CTSKCTSSCTSLCTSBMMP1 | |
| SCHEMBL6801548 | 0.89 | CTSS (0.35) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4704896 | 0.86 | CTSK (0.34) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4704688 | 0.86 | CTSL (0.33) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4699887 | 0.86 | CTSS (0.34) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4703317 | 0.86 | HRH3 (0.35) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4703269 | 0.85 | ATP4A (0.36) | CTSKCTSSCTSLMMP1 | |
| SCHEMBL4704824 | 0.85 | CTSK (0.36) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4703639 | 0.85 | CTSK (0.36) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-10-01 | — | — | EP | disclosed |