Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584128 | 0.79 | MEN1 (0.37) | LMNAALOX15HPGDHSD17B10MAPT | |
| SCHEMBL28338819 | 0.77 | ALDH1A1 (0.36) | ADRB1ADRA2AADRB3ADRA2BADRA2C | |
| SCHEMBL29722828 | 0.76 | CES2 (0.38) | LMNAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL2834212 | 0.76 | ALDH1A1 (0.52) | LMNAALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL775593 | 0.76 | CES2 (0.38) | LMNAMAPTRAB9AMEN1KMT2A | |
| SCHEMBL31550782 | 0.76 | ALDH1A1 (0.52) | LMNAALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL337809 | 0.75 | — | — | |
| SCHEMBL29368735 | 0.75 | — | — | |
| SCHEMBL9810705 | 0.74 | ALOX15 (0.38) | LMNAALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1145218 | 0.74 | ACHE (0.39) | LMNAALDH1A1CA2TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171417-B1 | METHODS FOR PREPARING 3-ARYLOXY-3-ARYLPROPYLAMINES AND INTERMEDIATES THEREOF | LILLY CO ELI (US) | 2005-11-09 | — | — | EP | claimed |
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-01 | — | — | US | disclosed |
| US-9255100-B2 | Substituted imidazopyridazines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-09 | — | — | US | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |
| EP-2383245-A2 | Method for continuous oxidation of thioethers | Bayer Technology Services GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| WO-2007009146-A1 | SUBSTITUTED 1-PHENYL IMIDAZOLES AS COX-I INHIBITORS | Universität Wien (AT) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | PADI4, PADI2, PADI6 | ADRB1 3715/4885ADRA2A 4166/4885ADRB3 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.