Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170703 | 0.86 | KDM4E (0.41) | KDM4EMEN1GFERKMT2ASIRT2 | |
| SCHEMBL4701677 | 0.85 | DHFR (0.39) | MEN1KMT2AMAPTMCHR1 | |
| SCHEMBL5611764 | 0.85 | DHFR (0.43) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL4700676 | 0.83 | MCHR1 (0.37) | MAPTMCHR1 | |
| SCHEMBL4704498 | 0.83 | MCHR1 (0.38) | MAPTALDH1A1MCHR1 | |
| SCHEMBL5612513 | 0.77 | GRM1 (0.46) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL5611544 | 0.73 | GRM1 (0.40) | KDM4EMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4166769 | 0.73 | MAPT (0.60) | KDM4EKMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL4703085 | 0.73 | ALDH1A1 (0.45) | KDM4EMEN1GFERKMT2ASIRT2 | |
| SCHEMBL1689154 | 0.73 | MCHR1 (0.39) | MAPTALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999132-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM, LLC (BM) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | disclosed |