Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707774 | 0.81 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL5621752 | 0.80 | NOD2 (0.53) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL4707041 | 0.79 | LMNA (0.37) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL4708671 | 0.77 | TDP1 (0.44) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL4707301 | 0.76 | TDP1 (0.43) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL4705529 | 0.76 | MTNR1A (0.43) | ALDH1A1KDM4ERXFP1MAPTSMN1; SMN2 | |
| SCHEMBL9203790 | 0.69 | MAPT (0.40) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL4705478 | 0.69 | KDM4E (0.36) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL17368516 | 0.69 | NOD2 (0.52) | MEN1KMT2AALDH1A1KDM4ERXFP1 | |
| SCHEMBL1983207 | 0.69 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-B1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1625129-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | Bayer HealthCare AG (DE) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004099212-A1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2004-11-18 | — | — | WO | disclosed |