Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 8/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 5/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706699 | 0.87 | RORB (0.42) | RORBP2RX7RORC | |
| SCHEMBL4706973 | 0.86 | RORB (0.44) | RORBP2RX7RORC | |
| SCHEMBL4759328 | 0.86 | RORB (0.43) | RORBP2RX7RORCPTGDR2 | |
| SCHEMBL4708468 | 0.85 | RORB (0.41) | RORBP2RX7RORCRPS6KA3 | |
| SCHEMBL4708752 | 0.85 | RORB (0.43) | RORBP2RX7RORCCRHR1RPS6KA3 | |
| SCHEMBL4708293 | 0.84 | RORB (0.40) | RORBP2RX7RORC | |
| SCHEMBL4705301 | 0.84 | RORB (0.42) | RORBP2RX7RORCPTGDR2 | |
| SCHEMBL4705134 | 0.81 | RORB (0.45) | RORBP2RX7RORCRPS6KA3PTGDR2 | |
| SCHEMBL4708736 | 0.81 | RORB (0.49) | RORBP2RX7RORCRPS6KA3PTGDR2 | |
| SCHEMBL4708689 | 0.78 | RORB (0.40) | RORBRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |