Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 10/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705055 | 0.92 | ALDH1A1 (0.34) | TACR1SMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL4705865 | 0.82 | ALDH1A1 (0.42) | RECQLTACR1SMN1; SMN2METALDH1A1 | |
| SCHEMBL4707918 | 0.81 | CDC7 (0.38) | TACR1HTT | |
| SCHEMBL4705841 | 0.79 | IDH1 (0.36) | SMN1; SMN2HTT | |
| SCHEMBL4705320 | 0.78 | SOS1 (0.34) | TACR1SMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL4707397 | 0.78 | P2RX7 (0.36) | RECQLTACR1SMN1; SMN2METALDH1A1 | |
| SCHEMBL4709657 | 0.76 | ALDH1A1 (0.35) | TACR1SMN1; SMN2TSHRALDH1A1HPGD | |
| SCHEMBL4707128 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2TSHRALDH1A1HPGDHTT | |
| SCHEMBL4705300 | 0.73 | ALDH1A1 (0.40) | SMN1; SMN2TSHRALDH1A1HPGDHTT | |
| SCHEMBL4707828 | 0.71 | CDC7 (0.42) | TACR1METALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |