Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LIPE | Q05469 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470989 | 0.88 | DRD1 (0.46) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL10005544 | 0.87 | LTA4H (0.45) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL11016705 | 0.83 | SMN1; SMN2 (0.72) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL240269 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL29494845 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL470990 | 0.77 | NOS3 (0.38) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL7172986 | 0.76 | SMN1; SMN2 (0.96) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL13211386 | 0.75 | NR4A1 (0.54) | SMN1; SMN2TSHRMAPK1CYP3A4 | |
| SCHEMBL471097 | 0.75 | AGXT (0.36) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL470986 | 0.75 | DRD1 (0.45) | DRD1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033091-A1 | PROCESS FOR PREPARING BENZOIC ACID ESTERS | 第一三共株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |
| WO-2010101164-A1 | PYRIDINE DERIVATIVE | 第一三共株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |