Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3216929 | 0.93 | SIGMAR1 (0.42) | SIGMAR1CTSDALDH1A1MAPK1KDM4E | |
| SCHEMBL3215576 | 0.87 | SIGMAR1 (0.44) | SIGMAR1CTSDALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL3210300 | 0.86 | SIGMAR1 (0.43) | SIGMAR1CTSDALDH1A1MAPTKDM4E | |
| SCHEMBL4718285 | 0.85 | CA2 (0.45) | SIGMAR1CTSDALDH1A1HPGDMAPK1 | |
| SCHEMBL4719286 | 0.85 | CTSD (0.43) | CTSDALDH1A1MAPK1KDM4ETACR1 | |
| SCHEMBL4715532 | 0.85 | CTSD (0.48) | SIGMAR1CTSDALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL3212426 | 0.84 | CA2 (0.45) | SIGMAR1CTSDALDH1A1HPGDMAPK1 | |
| SCHEMBL3209339 | 0.84 | CTSD (0.57) | CTSDALDH1A1MAPTKDM4E | |
| SCHEMBL3198015 | 0.84 | CTSD (0.42) | CTSDALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL3200551 | 0.84 | CTSD (0.47) | CTSDALDH1A1MAPTKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |