Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 2/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67998 | 0.73 | P2RY6 (0.33) | P2RY6CHRNB4CHRNA3TMEM97DRD5 | |
| SCHEMBL31711236 | 0.71 | P2RY6 (0.41) | NPC1RAB9AP2RY6ALDH1A1HSD17B10 | |
| SCHEMBL3200612 | 0.71 | P2RY6 (0.41) | NPC1RAB9AP2RY6ALDH1A1HSD17B10 | |
| SCHEMBL9392813 | 0.69 | P2RY6 (0.41) | P2RY6CYP3A4MAPTPTGS2DRD5 | |
| SCHEMBL5552767 | 0.65 | MAPT (0.42) | NPC1RAB9ACYP3A4MAPTALDH1A1 | |
| SCHEMBL4624307 | 0.64 | MAPT (0.46) | CYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL9562071 | 0.63 | RAB9A (0.35) | NPC1RAB9AP2RY6MAPTDRD5 | |
| SCHEMBL1987675 | 0.62 | CYP3A4 (0.71) | NPC1MTORRAB9AVCPCYP3A4 | |
| SCHEMBL27680960 | 0.62 | MAPT (0.53) | RAB9ACYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL27932094 | 0.62 | ALDH1A1 (0.56) | NPC1RAB9ACYP3A4ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493469-B2 | Piperidine inhibitors of Janus kinase 3 | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | claimed |
| EP-2727915-A1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | Concert Pharmaceuticals Inc. (US) | 2014-05-07 | — | — | EP | claimed |
| US-7244411-B2 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-07-17 | — | — | US | claimed |
| EP-1785729-A2 | A method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2007-05-16 | — | — | EP | claimed |
| US-20070099304-A1 | Method for the selective isolation of multiply-charged peptides applicable in the quantitative proteomics | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2007-05-03 | — | — | US | claimed |
| EP-1589341-A2 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CIGB) (CU) | 2005-10-26 | — | — | EP | claimed |
| US-20050176085-A1 | Method of selective peptide isolation for the identification and quantitative analysis of proteins in complex mixtures | CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA (CU) | 2005-08-11 | — | — | US | claimed |
| US-12024580-B2 | Resin composition suitable for printing and printing methods | Montanuniversität Leoben (AT) | 2024-07-02 | — | — | US | disclosed |
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | MELINTA SUBSIDIARY CORP. (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4356736-A2 | SYNTHESIS OF BORONATE SALTS | Melinta Therapeutics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-3604316-B1 | SYNTHESIS OF BORONATE SALTS | MELINTA THERAPEUTICS INC (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3540013-B1 | RESIN COMPOSITION SUITABLE FOR PRINTING AND PRINTING METHOD UTILIZING THE SAME | MONTANUNIV LEOBEN (AT) | 2022-05-25 | — | — | EP | disclosed |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | Roche Sequencing Solutions, Inc. (US) | 2022-02-01 | — | — | US | disclosed |
| WO-2005011573-A2 | NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS, INC. (US) | 2005-02-10 | — | — | WO | disclosed |
| WO-2005010075-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005000233-A2 | NOVEL THERAPEAUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS | AUSPEX PHARMACEUTICALS (US) | 2005-01-06 | — | — | WO | disclosed |
| EP-1485707-A2 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | HK Pharmaceuticals, Inc. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
| US-6677163-B1 | SIMPLE AND DURABLE IMMOBILIZATION OF BIOMOLECULES | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2004-01-13 | — | — | US | disclosed |
| WO-2003092581-A2 | CAPTURE COMPOUNDS, COLLECTIONS THEREOF AND METHODS FOR ANALYZING THE PROTEOME AND COMPLEX COMPOSITIONS | HK PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999757-B2 | Synthesis of boronate ester derivatives and uses thereof | ADH5, ADH1A, ADH7 | NPC1 1287/4885MTOR 1665/4885RAB9A 3139/4885 |
| US-11237156-B2 | Method and composition for detection of peptide cyclization using protein tags | CACYBP, VIP, PTMS | NPC1 4193/4885MTOR 3950/4885RAB9A 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.