Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 14/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101991 | 0.94 | TRPA1 (0.32) | TRPA1TRPV4 | |
| SCHEMBL4720381 | 0.92 | TRPA1 (0.33) | EIF4EBP1TRPA1TRPV4 | |
| SCHEMBL4722283 | 0.84 | HPGDS (0.35) | EIF4EBP1TRPA1HPGDSPRMT5WDR77 | |
| SCHEMBL4719630 | 0.79 | CTSS (0.33) | — | |
| SCHEMBL4718895 | 0.77 | CYP3A4 (0.32) | — | |
| SCHEMBL4723491 | 0.69 | P2RX7 (0.36) | — | |
| SCHEMBL4723495 | 0.69 | P2RX7 (0.36) | — | |
| SCHEMBL4722298 | 0.69 | PDE4A (0.35) | — | |
| SCHEMBL4722940 | 0.69 | P2RX7 (0.40) | — | |
| SCHEMBL4722935 | 0.69 | P2RX7 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963282-A1 | SULFOXIMINE-SUBSTITUTED PYRIMIDINES , THEIR PREPARATION AND USE AS DRUGS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007071455-A1 | SULFOXIMINE-SUBSTITUTED PYRIMIDINES , THEIR PREPARATION AND USE AS DRUGS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | WO | disclosed |