Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 10/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.31 |
| ▸ | EIF4EBP1 | Q13541 | 4/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721863 | 0.92 | EIF4EBP1 (0.33) | TRPA1TRPV4EIF4EBP1 | |
| SCHEMBL14101991 | 0.92 | TRPA1 (0.32) | TRPA1TRPV4 | |
| SCHEMBL4719630 | 0.76 | CTSS (0.33) | KDM4E | |
| SCHEMBL4722283 | 0.76 | HPGDS (0.35) | TRPA1EIF4EBP1 | |
| SCHEMBL4718895 | 0.76 | CYP3A4 (0.32) | — | |
| SCHEMBL4722298 | 0.70 | PDE4A (0.35) | — | |
| SCHEMBL4720845 | 0.70 | PDE4A (0.36) | — | |
| SCHEMBL4719850 | 0.69 | PDE4A (0.39) | — | |
| SCHEMBL4722935 | 0.67 | P2RX7 (0.40) | RORC | |
| SCHEMBL4722940 | 0.67 | P2RX7 (0.40) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |