Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723755 | 0.85 | PIN1 (0.55) | PIN1KMT2ANPC1MEN1SGMS2 | |
| SCHEMBL29206007 | 0.80 | ALDH1A1 (0.49) | PIN1KMT2ANPC1MEN1RAB9A | |
| SCHEMBL5594949 | 0.80 | HTR1A (0.53) | PIN1KMT2ANPC1MEN1SGMS2 | |
| SCHEMBL16879230 | 0.77 | KMT2A (0.60) | KMT2ANPC1MEN1RAB9ACTSB | |
| SCHEMBL31554583 | 0.77 | ABCG2 (0.48) | KMT2AMEN1 | |
| SCHEMBL311213 | 0.76 | MEN1 (0.48) | PIN1KMT2ANPC1MEN1RAB9A | |
| SCHEMBL1486647 | 0.76 | BACE1 (0.50) | PIN1KMT2ANPC1MEN1RAB9A | |
| SCHEMBL6823293 | 0.75 | HTR1A (0.49) | PIN1KMT2ANPC1MEN1SGMS2 | |
| SCHEMBL30015078 | 0.75 | NPC1 (0.68) | PIN1KMT2ANPC1MEN1SGMS2 | |
| SCHEMBL2305236 | 0.75 | NPC1 (0.68) | PIN1KMT2ANPC1MEN1SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101330916-A | Substituted imidazoquinolines, imidazonaphthyridines, and imidazopyridines, compositions, and methods thereof | COLEY PHARMACEUTICAL INC (US) | 2008-12-24 | — | — | CN | disclosed |
| EP-1968587-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | Coley Pharmaceutical, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |