SCHEMBL472574

SCHEMBL472574

CSN1C(=O)CC(=O)N(SC)C1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL774525 0.88
SCHEMBL2680434 0.72 F2 (0.31)
SCHEMBL26061612 0.72 PLA2G7 (0.33)
SCHEMBL7761904 0.71
SCHEMBL3691197 0.70 MAPT (0.40) MEN1MAPTKMT2A
SCHEMBL19258471 0.67 BRD4 (0.40) MEN1KMT2A
SCHEMBL8432494 0.65
SCHEMBL10969459 0.65 NOTUM (0.51) MEN1MAPTKMT2A
SCHEMBL1165632 0.62 MAPT (0.44) MEN1MAPTKMT2A
SCHEMBL5065703 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-7429274-B2 Agent and method for the oxidative coloring of keratin fibers WELLA AG (DE) 2008-09-30 US claimed
EP-1432388-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2008-06-18 EP claimed
US-7374580-B2 Dyeing compositions comprising A 1,2-indandione derivative L'OREAL S.A. (FR) 2008-05-20 US claimed
EP-1387659-B1 INITIATOR SYSTEM FOR ACID DENTAL FORMULATIONS 3M ESPE AG (DE) 2008-05-07 EP claimed
US-7367993-B2 Dyeing compositions comprising at least one 1,3-indandione derivative L'OREAL S.A. (FR) 2008-05-06 US claimed
EP-1502580-B1 Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles OREAL (FR) 2008-01-23 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
US-20050060817-A1 Use of ninhydrin derivatives bearing an unsaturated system for dyeing keratin material L'OREAL S.A. (FR) 2005-03-24 US claimed
US-20050060818-A1 Composition and method of dyeing keratin fibers comprising at least one heteroalkyl group comprising at least one ninhydrin derivative L'OREAL S.A. (FR) 2005-03-24 US claimed
US-20050050652-A1 Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050654-A1 Process for dyeing keratin fibers with at least one ninhydrin derivative L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050653-A1 Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050651-A1 Use of at least one ninhydrin derivative for dyeing L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050655-A1 Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative L'OREAL S.A. (FR) 2005-03-10 US claimed
EP-1139990-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2004-05-06 EP claimed
EP-1139988-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2002-09-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050060817-A1 Use of ninhydrin derivatives bearing an unsaturated system for dyeing keratin material KRT18, NISCH, JUP MEN1 3291/4885MAPT 3422/4885KMT2A 2796/4885
US-20050050653-A1 Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings KRT18, NISCH, JUP MEN1 390/4885MAPT 1692/4885KMT2A 3253/4885
US-20050050652-A1 Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione KRT18, HKDC1, JUP MEN1 2318/4885MAPT 759/4885KMT2A 798/4885
US-20050050654-A1 Process for dyeing keratin fibers with at least one ninhydrin derivative KRT18, DSG1, ACR MEN1 1651/4885MAPT 1010/4885KMT2A 2571/4885
US-20050060818-A1 Composition and method of dyeing keratin fibers comprising at least one heteroalkyl group comprising at least one ninhydrin derivative KRT18, C9, S100A6 MEN1 2388/4885MAPT 2347/4885KMT2A 4102/4885
US-20050050655-A1 Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative KRT18, JUP, NISCH MEN1 2818/4885MAPT 2114/4885KMT2A 885/4885
US-20050050651-A1 Use of at least one ninhydrin derivative for dyeing NISCH, NPM1, NCDN MEN1 542/4885MAPT 65/4885KMT2A 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.