Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.44 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729520 | 0.92 | MOGAT2 (0.44) | PKMATMBRD4CREBBPMOGAT2 | |
| SCHEMBL4728002 | 0.91 | MOGAT2 (0.45) | PKMATMBRD4CREBBPMOGAT2 | |
| SCHEMBL4725656 | 0.90 | KMT2A (0.45) | PKMBRD4MAPTTHRBSMN1; SMN2 | |
| SCHEMBL4729847 | 0.89 | MOGAT2 (0.46) | PKMATMBRD4MOGAT2MGAT2 | |
| SCHEMBL4725665 | 0.88 | GHSR (0.44) | PKMATMBRD4CREBBPMOGAT2 | |
| SCHEMBL4727604 | 0.86 | MEN1 (0.47) | PKMBRD4MOGAT2MGAT2MAPT | |
| SCHEMBL4729811 | 0.85 | ALDH1A1 (0.50) | MOGAT2MGAT2MAPTDRD3HTT | |
| SCHEMBL4779866 | 0.84 | DRD3 (0.49) | PKMMOGAT2MGAT2DRD3HTT | |
| SCHEMBL4727679 | 0.84 | ALDH1A1 (0.48) | PKMMAPTTP53SMN1; SMN2DRD3 | |
| SCHEMBL4729815 | 0.83 | ALDH1A1 (0.47) | BRD4MOGAT2MGAT2MAPTDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |